User-facing operations |
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Calculate a melted similarity matrix. |
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Calculate similarities given pairs of rows |
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Collate several subsets of a melted similarity matrix, required for computing metrics. |
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Compute metrics. |
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Report p-values for metrics |
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Widen a symmetric melted similarity matrix. |
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Plot a melted similarity matrix. |
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Annotation and filtering operations |
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Annotate a melted similarity matrix. |
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Filter a melted similarity matrix to remove or keep specified rows. |
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Filter a melted similarity matrix to keep pairs with the same values in specific columns. |
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Filter a melted similarity matrix to keep pairs with the same values in specific columns, and keep only some of these pairs. |
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Filter a melted similarity matrix to keep pairs with the same values in specific columns, and other constraints. |
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Read-write operations |
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Read similarity matrix. |
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Write similarity matrix. |
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Class operations |
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Constructor for |
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Validator for |
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Restorer for |
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Helper functions |
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Get row annotations. |
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Drop row annotations. |
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Preprocess data.
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Helper function to compute metrics. |
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Compute null distribution for a set of metrics |
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Compute null distribution of metrics |
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Compute p-value against null distribution |
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Bin values into increasingly wider bins |
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Sparse operations |
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Compute similarity between pairs of rows of a matrix |
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Compute similarity between pairs of rows of a matrix |
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Compute cross product between two sets of rows of a matrix. |
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Datasets |
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Cell Painting dataset of CRISPR perturbations. |
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Quality metrics for Cell Painting dataset of CRISPR perturbations. |
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Package |
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matric: Metrics for Similarity Matrices |